Anaphylaxis:
Severe, sometimes life-threatening allergic reaction that can cause extreme swelling (including swelling of the lips and/or throat), hives, vomiting, and other extreme adverse physical reactions and, if untreated, may interfere with heart function. Anaphylaxis can be a reaction to any allergen, but the most common triggers are food, medication, insect stings, and latex. Anaphylaxis typically occurs shortly after contact with or ingestion of the triggering allergen, but it can occur at any time.
Anaphylactic Shock:
Most severe type of anaphylaxis, in which the body’s systemic response to an allergen results in a drastic drop in blood pressure. It may result in loss of consciousness, and if not treated promptly, may lead to death.
Diclofenac:
Sold under the brand names Voltaren© and Cataflam©, Diclofenac is an NSAID used to treat the symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Unlike Celebrex, Diclofenac is not a selective COX-2 Inhibitor.
Familial Adenomatous Polyposis:
A very rare, genetic condition in which the patient develops colon and rectal polyps that often lead to premature development of colorectal cancer. FAP is treated with surgery to remove existing polyps, and patients with FAP must be monitored regularly to check for regrowth of the polyps. Celebrex is currently approved for the treatment of FAP, and has been shown to reduce polyp growth when used in conjunction with standard treatments.
Osteoarthritis:
A disease of the joints, most commonly associated with old age and/or repetitive joint stress, in which the cartilage that normally cushions a joint’s movements breaks down, causing pain and inflammation in the affected joints.
Rheumatoid Arthritis:
A disease in which the immune system attacks the cartilage that cushions a joint’s movements, resulting in pain and inflammation. RA can occur in children as well as adults; it is referred to as Juvenile Rheumatoid Arthritis when it affects patients ages 2-17.
Sulfonamide:
Any of a class of drugs, typically called “sulfa” drugs, that are derived from sulfonic acid. Sulfonamides are most commonly used to treat bacterial infections, hypertension, and gout.
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